What is Pharmacogenomics (PGx)
Many commonly prescribed medications used to treat everyday ailments can be metabolized differently based on an individual’s inherited genetic variants. Pharmacogenomic testing blends the study of drugs called Pharmacology, with the study of genetic mapping and DNA sequencing called Genomics. Testing helps physicians select effective, safe medications and doses that are tailored to an individual’s specific genetic makeup.
There are several common genetic variations that substantially reduce or increase the functionality of enzymes involved in metabolizing frequently prescribed drugs. If a patient’s genetic profile contains one or more of these variants, it may significantly affect their ability to break down and absorb many commonly prescribed medications. PGx testing analyzes how the genetic makeup of an individual affects his/her response to drugs in order to avoid reduced efficacy of the medication or increased risk of adverse drug reactions.
Some available genetic tests
Determine which drugs (beta blockers, calcium channel blockers, blood-thinners, etc.) work best for your patient based on individual genetic variants.
Pain Management Panel
Identifies genetic traits that affect how an individual will react to the effects of certain types of frequently prescribed pain medications.
Mental Health Panel
Reveal genetic characteristics that affect the metabolism and efficacy of psychiatric medications.